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Jerrold R Turner Selected Research

Myosin-Light-Chain Kinase

5/2022Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn's disease.
1/2021A novel tumor suppressor role of myosin light chain kinase splice variants through downregulation of the TEAD4/CD44 axis.
11/2020Myosin light chain kinase is a potential target for hypopharyngeal cancer treatment.
1/2017Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression.
8/2013TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.
9/2012Inhibition of long myosin light-chain kinase activation alleviates intestinal damage after binge ethanol exposure and burn injury.
12/2006Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application.
10/2006Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo.
5/2006Inhibiting myosin light chain kinase retards the growth of mammary and prostate cancer cells.
2/2006Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease.
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Jerrold R Turner Research Topics

Disease

17Inflammation (Inflammations)
01/2022 - 03/2004
16Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2022 - 03/2004
15Colitis
01/2021 - 10/2006
14Infections
01/2020 - 09/2004
13Diarrhea
01/2020 - 03/2005
7Ulcerative Colitis
11/2021 - 03/2005
7Neoplasms (Cancer)
01/2021 - 03/2005
6Intestinal Diseases (Diseases, Intestinal)
01/2019 - 07/2002
5Sepsis (Septicemia)
01/2016 - 02/2004
4Crohn Disease (Crohn's Disease)
05/2022 - 06/2005
4Celiac Disease (Celiac Sprue)
01/2020 - 08/2014
4Wounds and Injuries (Trauma)
06/2012 - 04/2005
4Adenoma (Adenomas)
09/2010 - 10/2008
3Carcinogenesis
01/2021 - 01/2007
3Graft vs Host Disease (Graft-Versus-Host Disease)
01/2020 - 01/2012
3Body Weight (Weight, Body)
01/2020 - 01/2007
3Bacterial Infections (Bacterial Infection)
10/2014 - 10/2008
3Colonic Neoplasms (Colon Cancer)
06/2010 - 01/2007
2Coronary Artery Disease (Coronary Atherosclerosis)
01/2021 - 01/2021
2Salmonella Infections (Salmonellosis)
01/2020 - 06/2015
2Obesity
10/2019 - 04/2015
2Malnutrition (Nutritional Deficiencies)
08/2017 - 01/2016
2Necrotizing Enterocolitis
02/2017 - 05/2013
2Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
01/2017 - 12/2009
2Dysbiosis
03/2015 - 10/2014
2Burns
10/2014 - 09/2012
2Herpes Zoster
01/2010 - 10/2006
2Cystic Fibrosis (Mucoviscidosis)
07/2009 - 05/2009
2Hepatocellular Carcinoma (Hepatoma)
02/2009 - 03/2005
2Critical Illness (Critically Ill)
02/2008 - 06/2006
1Hypopharyngeal Neoplasms
11/2020
1Common Variable Immunodeficiency
01/2020
1Dumping Syndrome (Syndrome, Dumping)
10/2019
1Diabetes Mellitus
10/2019
1Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2019
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
01/2019

Drug/Important Bio-Agent (IBA)

14CytokinesIBA
01/2022 - 03/2004
13Myosin-Light-Chain KinaseIBA
05/2022 - 04/2005
11OccludinIBA
11/2019 - 10/2005
8Proteins (Proteins, Gene)FDA Link
08/2017 - 10/2005
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2019 - 10/2006
5Claudin-2IBA
10/2020 - 10/2008
5Myosin Light Chains (Myosin Essential Light Chain)IBA
01/2019 - 04/2005
5Messenger RNA (mRNA)IBA
01/2018 - 12/2009
5Tight Junction ProteinsIBA
06/2017 - 10/2008
4Protein Isoforms (Isoforms)IBA
01/2021 - 03/2008
4Anti-Bacterial Agents (Antibiotics)IBA
03/2015 - 06/2006
3Ethanol (Ethyl Alcohol)IBA
04/2016 - 09/2012
3Myosin Type IIIBA
08/2013 - 10/2005
3Claudin-1IBA
01/2010 - 10/2008
3Pharmaceutical PreparationsIBA
02/2008 - 01/2005
3Phosphotransferases (Kinase)IBA
10/2006 - 07/2002
3Peptides (Polypeptides)IBA
10/2005 - 07/2002
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2021 - 01/2021
2InterferonsIBA
01/2021 - 08/2014
2claudin 15IBA
01/2020 - 01/2017
2EnzymesIBA
01/2019 - 01/2007
2Glutens (Glutelin)IBA
01/2017 - 09/2015
2AntibodiesIBA
09/2015 - 10/2006
2Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
03/2015 - 08/2013
2Interleukin-6 (Interleukin 6)IBA
10/2014 - 09/2012
2ML 7IBA
08/2014 - 05/2006
2Dextran SulfateIBA
08/2013 - 06/2010
2Type II Tumor Necrosis Factor ReceptorsIBA
08/2013 - 10/2006
2ClaudinsIBA
05/2013 - 05/2011
2AzoxymethaneIBA
06/2010 - 01/2007
2Fas Ligand Protein (Fas Ligand)IBA
06/2010 - 05/2010
2LigandsIBA
05/2010 - 03/2004
2Serotonin (5 Hydroxytryptamine)IBA
12/2009 - 04/2005
2Interleukin-8 (Interleukin 8)IBA
09/2009 - 10/2008
2AnionsIBA
07/2009 - 05/2009
2ChloridesIBA
05/2009 - 02/2007
2Phenobarbital (Luminal)FDA Link
02/2009 - 02/2007
2LipopolysaccharidesIBA
10/2008 - 03/2008
2Lymphotoxin-alpha (Lymphotoxin)IBA
06/2007 - 06/2005
2Glycoproteins (Glycoprotein)IBA
06/2007 - 06/2005
2LectinsIBA
01/2007 - 01/2005
2Lymphotoxin beta ReceptorIBA
06/2005 - 03/2004
1Carrier Proteins (Binding Protein)IBA
05/2022
1Tacrolimus (Prograf)FDA LinkGeneric
05/2022
1Pattern Recognition ReceptorsIBA
01/2022
1Leukocyte L1 Antigen Complex (Calgranulin)IBA
11/2021
1C-Reactive ProteinIBA
01/2021
1Atorvastatin (Lipitor)FDA Link
01/2021
1SmokeIBA
10/2020
1CationsIBA
10/2020
1CadmiumIBA
01/2020
1LaccaseIBA
01/2020
1Caspase 3 (Caspase-3)IBA
11/2019
1Fenofibrate (CiL)FDA LinkGeneric
10/2019
1Castor Oil (Oil, Castor)IBA
10/2019
1Phenolsulfonphthalein (Phenol Red)IBA
10/2019
1Glucose (Dextrose)FDA LinkGeneric
10/2019
1Pentetic Acid (DTPA)FDA LinkGeneric
10/2019
1Dihydrotachysterol (AT 10)IBA
10/2019
1InterleukinsIBA
01/2019
1Immunoglobulin E (IgE)IBA
01/2018

Therapy/Procedure

11Therapeutics
11/2021 - 01/2005
1Oral Administration
01/2020
1Hematopoietic Stem Cell Transplantation
01/2019